Professor Stephen Mackinnon works in the bone marrow and stem cell program at University College London. He attended medical school at the University of Glasgow. He subsequently trained in Internal Medicine and Haemato-oncology in Glasgow. This was followed by a transplant fellowship at the Hammersmith Hospital in London where he developed an interest in graft-versus-leukaemia reactions. In 1990 he moved to Memorial Sloan Kettering Cancer Center in New York to continue this work in both the clinic and the lab. He made the use of donor lymphocytes less toxic by limiting the T cell dose administered to transplant recipients allowing separation of graft-versus-leukaemia responses from graft-versus-host disease.
In 1995 he returned to University College London to his current position. He became the Clinical and Academic Head of Department at the Royal Free Campus in 2004 and has recruited a highly effective and productive group of clinical and laboratory haematologists. He is an expert in the treatment of leukaemia, lymphoma, myeloma and in the use of bone marrow and stem cell transplantation to promote long-term cure of haematological malignancies. Current research interests include adoptive immunotherapy and immune reconstitution following allogeneic stem cell transplantation.