Professor Trevor Graham leads the Evolution and Cancer laboratory at the Barts Cancer Institute, QMUL in London, UK. The lab focuses on measuring the dynamics and drivers of somatic evolution in human tissues, particular in the gastrointestinal tract, and tries to use these measures to better predict cancer development risk in premalignant disease, and determine prognosis and optimise treatment regimes in established cancers.
Trevor has a long-standing interest in colorectal cancer evolution, and his recent work has challenged the way in which we understand the development of this common cancer type. The major funders of his lab are Cancer Research UK and the Wellcome Trust.
Trevor’s background is in mathematics, and during his doctoral and postdoctoral training he ventured into the wet-lab where he learnt molecular biology approaches (mainly genetics) for studying cancer evolution. His multidisciplinary lab combines expertise in both theory (maths, physics, computer science, evolutionary biology) together with empirical measurement (molecular genetics, histopathology, bioinformatics).