Professor Trevor Graham leads the Evolution and Cancer laboratory at the Barts Cancer Institute, QMUL in London, UK. The lab focuses on measuring the dynamics and drivers of somatic evolution in human tissues, particular in the gastrointestinal tract, and tries to use these measures to better predict prognosis and optimise treatment regimes.
Trevor’s background is in mathematics, and during his doctoral and postdoctoral training he ventured into the wet-lab where he learnt molecular biology approaches (mainly genetics) for studying cancer evolution. His multidisciplinary lab combines expertise in both theory (maths, physics, computer science, evolutionary biology) together with empirical measurement (molecular genetics, histopathology, bioinformatics) and it is this unique synergy of skills that provides the underpinning to the laboratory’s work.
Trevor has a long-standing interest in colorectal cancer evolution, and his recent work has challenged the way in which we understand the development of this common cancer type.